The program is broadcast live over most NBC stations from 6:30 p.m. Previous anchors have included John Chancellor, David Brinkley, Tom Brokaw and Brian Williams. Since 2015, the broadcast has been anchored by Lester Holt on weeknights, José Díaz-Balart on Saturday and Kate Snow on Sunday. Select Los Angeles–based editions broadcast from The Brokaw News Center in Universal City, California, or when broadcasting from Washington, D.C., either from the NBC News bureau based at WRC-TV in the Tenleytown neighborhood, or NBC's secondary studio overlooking Capitol Hill.

NBC Nightly News is produced from Studio 1A at NBC Studios at 30 Rockefeller Center in New York City. First aired on August 3, 1970, the program is currently the second most watched network newscast in the United States, behind ABC's World News Tonight.

NBC Nightly News (titled as NBC Nightly News with Lester Holt for its weeknight broadcasts since June 22, 2015) is the flagship daily evening television news program for NBC News, the news division of the NBC television network in the United States.

NBC Nightly News with Lester Holt (2015–present).

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